A three-dimensional (3D) numerical model of fixed Oscillating Water Column system (OWC) is presented and validated. The steady-state potential flow boundary value problem due to regular wave interaction with the OWC is solved by a first order mixed distribution panel method. Ocean response predictions are derived using a deterministic statistical model based on a spectral analysis method. The model validation focusses on diffraction predictions and involves convergence tests and numerical comparisons with independent potential flow computations. Predictions of both regular and irregular wave responses are also compared against experimental results. Sample results including the yearly-averaged power conversion efficiency are presented in the final section to illustrate the method’s suitability to a 3D hydrodynamic design optimisation.