The blade is the key component for energy capture in horizontal axis tidal current turbine, and the blade’s design is directly related to the efficiency of the power generation device. The seawater flow velocity is a crucial parameter for blade design. Since the seawater velocity changes constantly, it is extremely important to determine the design velocity of the blade. This article proposes a calculation method for the design velocity of the blade so that the designed blade can achieve better energy collection efficiency under a variable flow velocity. This study performed the following investigations: (1) The author tested and analyzed the seawater velocity variation at the experimental site, determining the designed flow velocity via calculations; (2) The author combined the blade element momentum and Wilson’s optimization design method using the MATLAB software to calculate the blade shape parameters and predict the performance under a number of different flow velocity forecasts; (3) When testing the device under sea conditions, the experimental results showed that the performance capture devices and digital projections are basically the same, which verifies the validity and effectiveness of the design method.