The aim of the study is to evaluate the parametric effect of a power take-off (PTO) system on an integration system of an oscillating buoy wave energy device with a pile-restrained floating breakwater. To consider the viscous effect, the study is carried out with three conditions using OpenFOAM, i.e., the linear optimal PTO system, the fixed PTO damping coefficient, and the Coulomb PTO system. The results show that the maximum wave energy capture ratio (CWR) of the device can merely reach 0.35 in the present work, when considering the viscous effect. This result is smaller than that obtained from potential flow. In addition, the linear optimal PTO coefficient under viscous flow should be larger than the theoretical optimal coefficient in terms of the potential flow. A comparison of the Coulomb damping model and the linear damping model also shows that the Coulomb damping model has a good performance in terms of both wave energy capture efficiency and coastal protection. Hence, the effect of the PTO system on such an integration system can be an essential factor to achieve an optimal design.